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Image Search Results
Journal: International Journal of Nanomedicine
Article Title: Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood–brain barrier
doi: 10.2147/IJN.S54750
Figure Lengend Snippet: In vivo blood–brain barrier (BBB) penetration. Notes: Representative fluorescence photomicrographs of immunohistochemistry on brain sections, of the specified area (marked with orange box) using a 6× Histag antibody to detect the TIMP-1-Histag fusion protein. The nucleus was labeled with DAPI. The TIMP-1 NPs + Ps80 group shows labeling indicating BBB penetration of TIMP-1 NPs + Ps80 as indicated by white arrows. Abbreviations: TIMP, tissue inhibitor of matrix metalloproteinases; DAPI, 4′,6-diamidino-2-phenylindole; NPs, nanoparticles; Ps80, polysorbate 80; PBS, phosphate-buffered saline.
Article Snippet: Recombinant mouse TIMP-1 with a 6×
Techniques: In Vivo, Fluorescence, Immunohistochemistry, Labeling, Saline